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Target
Neuraminidase
Ligand
BDBM50009296
Substrate
n/a
Meas. Tech.
ChEMBL_1335031 (CHEMBL3239462)
IC50
3100±n/a nM
Citation
 Abdel-Mageed, WM; Bayoumi, SA; Chen, C; Vavricka, CJ; Li, L; Malik, A; Dai, H; Song, F; Wang, L; Zhang, J; Gao, GF; Lv, Y; Liu, L; Liu, X; Sayed, HM; Zhang, L Benzophenone C-glucosides and gallotannins from mango tree stem bark with broad-spectrum anti-viral activity. Bioorg Med Chem 22:2236-43 (2014) [PubMed]  Article 
Target
Name:
Neuraminidase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
52019.94
Organism:
Influenza A virus
Description:
ChEMBL_108266
Residue:
469
Sequence:
MNPNQKIITIGSVSLTIATVCFLMQIAILATTVTLHFKQHECDSPASNQVMPCEPIIIERNITEIVYLNNTTIEKEICPKVVEYRNWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPGKCYQFALGQGTTLDNKHSNDTVHDRIPHRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCITGDDKNATASFIYDGRLVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGRADTRILFIEEGKIVHISPLSGSAQHIEECSCYPRYPGVRCICRDNWKGSNRPVVDINMEDYSIDSSYVCSGLVGDTPRNDDSSSNSNCRNPNNERGTQGVKGWAFDNGNDLWMGRTISKESRSGYETFKVIGGWSTPNSKSQVNRQVIVDNNNWSGYSGIFSVEGKSCINRCFYVELIRGRPQETRVWWTSNSIVVFCGTSGTYGTGSWPDGANINFMPI
  
Inhibitor
Name:
BDBM50009296
Synonyms:
LANINAMIVIR | R-125489
Type:
Small organic molecule
Emp. Form.:
C13H22N4O7
Mol. Mass.:
346.3364
SMILES:
[H][C@]1(OC(=C[C@H](NC(N)=N)[C@H]1NC(C)=O)C(O)=O)[C@H](OC)[C@H](O)CO |r,c:3|
Structure:
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