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Target
Ornithine decarboxylase
Ligand
BDBM50009353
Substrate
n/a
Meas. Tech.
ChEMBL_1344645 (CHEMBL3254307)
Ki
2700000±n/a nM
Citation
 Bey, P; Danzin, C; Van Dorsselaer, V; Mamont, P; Jung, M; Tardif, C Analogues of ornithine as inhibitors of ornithine decarboxylase. New deductions concerning the topography of the enzyme's active site. J Med Chem 21:50-5 (1978) [PubMed]  Article 
Target
Name:
Ornithine decarboxylase
Synonyms:
DCOR_RAT | Odc | Odc1
Type:
PROTEIN
Mol. Mass.:
51037.04
Organism:
Rattus norvegicus
Description:
ChEMBL_1344641
Residue:
461
Sequence:
MGSFTKEEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDVLKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPPERIIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMGTEVGFSMYLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQTGSDDEDESNEQTLMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCSLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRSMWQLMKQIQSHGFPPEVEEQDVGTLPMSCAQESGMDRHPAACASASINV
  
Inhibitor
Name:
BDBM50009353
Synonyms:
1,5,10-triazadecane | 4-azaoctamethylenediamine | 4-azaoctane-1,8-diamine | CHEMBL19612 | N-(3-aminopropyl)butane-1,4-diamine | spermidine
Type:
Small organic molecule
Emp. Form.:
C7H19N3
Mol. Mass.:
145.2459
SMILES:
NCCCCNCCCN
Structure:
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