Reaction Details Report a problem with these data
Target
Acrosin
Ligand
BDBM50010109
Substrate
n/a
Meas. Tech.
ChEMBL_1344334 (CHEMBL3257004)
Ki
440±n/a nM
Citation
 Parrish, RF; Straus, JW; Paulson, JD; Polakoski, KL; Tidwell, RR; Geratz, JD; Stevens, FM Structure-activity relationships for the inhibition of acrosin by benzamidine derivatives. J Med Chem 21:1132-6 (1979) [PubMed]  Article 
Target
Name:
Acrosin
Synonyms:
53 kDa fucose-binding protein | ACR | ACRO_PIG | Acrosin heavy chain | Acrosin light chain
Type:
PROTEIN
Mol. Mass.:
45383.66
Organism:
Sus scrofa
Description:
ChEMBL_108297
Residue:
415
Sequence:
MLPTAVLLVLAVSVAARDNATCDGPCGLRFRQKLESGMRVVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRLIFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPGCLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIRSTNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVGCARAKRPGVYTSTWPYLNWIASKIGSNALQMVQLGTPPRPSTPAPPVRPPSVQTPVRPPWYFQRPPGPSQQPGSRPRPPAPPPAPPPPPPPPPPPPPPPPPPPQQVSAKPPQALSFAKRLQQLIEALKGTAFSSGRSYYETETTDLQELPAS
  
Inhibitor
Name:
BDBM50010109
Synonyms:
CHEMBL2418035
Type:
Small organic molecule
Emp. Form.:
C15H14Cl2N4O
Mol. Mass.:
337.204
SMILES:
NC(=N)c1cccc(COc2c(Cl)cc(cc2Cl)C(N)=N)c1
Structure:
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