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Target
Melatonin receptor type 1B
Ligand
BDBM50114704
Substrate
n/a
Meas. Tech.
ChEMBL_1352262 (CHEMBL3268980)
Ki
0.330000±n/a nM
Citation
 Zlotos, DP; Jockers, R; Cecon, E; Rivara, S; Witt-Enderby, PA MT1 and MT2 melatonin receptors: ligands, models, oligomers, and therapeutic potential. J Med Chem 57:3161-85 (2014) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Homo sapiens (Human)
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM50114704
Synonyms:
CHEMBL33549 | N-(2-(5-methoxy-2-(3-methoxybenzyl)benzofuran-3-yl)ethyl)acetamide | N-{2-[5-Methoxy-2-(3-methoxy-benzyl)-benzofuran-3-yl]-ethyl}-acetamide
Type:
Small organic molecule
Emp. Form.:
C21H23NO4
Mol. Mass.:
353.4116
SMILES:
COc1cccc(Cc2oc3ccc(OC)cc3c2CCNC(C)=O)c1
Structure:
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