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Target
5-hydroxytryptamine receptor 2C
Ligand
BDBM50013113
Substrate
n/a
Meas. Tech.
ChEMBL_1350021 (CHEMBL3270821)
Ki
197±n/a nM
Citation
 Eliás, O; Agai-Csongor, E; Domány, G; Keseru, GM; Gere, A; Kiss, B; Hellinger, E; Vastag, M; Gyertyán, I Design of novel multiple-acting ligands towards SERT and 5-HT2C receptors. Bioorg Med Chem Lett 24:2118-22 (2014) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2C
Synonyms:
5-HT2C | 5-hydroxytryptamine receptor 2C | 5-hydroxytryptamine receptor 2C (5HT2c) | 5HT2C_RAT | 5ht1c | Htr1c | Htr2c | Serotonin (5-HT) receptor | Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
Type:
Enzyme
Mol. Mass.:
51935.10
Organism:
Rattus norvegicus (Rat)
Description:
P08909
Residue:
460
Sequence:
MVNLGNAVRSLLMHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALSIVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIYVLRRQTLMLLRGHTEEELANMSLNFLNCCCKKNGGEEENAPNPNPDQKPRRKKKEKRPRGTMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRHTNERVARKANDPEPGIEMQVENLELPVNPSNVVSERISSV
  
Inhibitor
Name:
BDBM50013113
Synonyms:
CHEMBL3261705
Type:
Small organic molecule
Emp. Form.:
C25H27Cl2N3O3
Mol. Mass.:
488.406
SMILES:
COc1ccc(NC(=O)Nc2ccc(Cl)c(Cl)c2)cc1OC(CCN(C)C)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: