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Target
Epsin-1
Ligand
BDBM50013327
Substrate
n/a
Meas. Tech.
ChEMBL_1348519 (CHEMBL3267161)
IC50
46000±n/a nM
Citation
 Yoon, Y Small chemicals with inhibitory effects on PtdIns(3,4,5)P3 binding of Btk PH domain. Bioorg Med Chem Lett 24:2334-9 (2014) [PubMed]  Article 
Target
Name:
Epsin-1
Synonyms:
EH domain-binding mitotic phosphoprotein | EPN1 | EPN1_HUMAN | EPS-15-interacting protein 1
Type:
PROTEIN
Mol. Mass.:
60270.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_108306
Residue:
576
Sequence:
MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQPPSCGPEDDAQLQLALSLSREEHDKEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL
  
Inhibitor
Name:
BDBM50013327
Synonyms:
CHEMBL3263343
Type:
Small organic molecule
Emp. Form.:
C4H5N2O5P
Mol. Mass.:
192.0667
SMILES:
OC(=O)c1cc(n[nH]1)P(O)(O)=O
Structure:
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