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Target
Elongin-C
Ligand
BDBM50446138
Substrate
n/a
Meas. Tech.
ChEMBL_1350284 (CHEMBL3267622)
IC50
4100±n/a nM
Citation
 Guo, W; Wisniewski, JA; Ji, H Hot spot-based design of small-molecule inhibitors for protein-protein interactions. Bioorg Med Chem Lett 24:2546-54 (2014) [PubMed]  Article 
Target
Name:
Elongin-C
Synonyms:
ELOC | ELOC_HUMAN | Elongin 15 kDa subunit | Elongin-C | RNA polymerase II transcription factor SIII subunit C | SIII p15 | TCEB1 | Transcription elongation factor B polypeptide 1
Type:
PROTEIN
Mol. Mass.:
12466.49
Organism:
Homo sapiens (Human)
Description:
ChEMBL_108414
Residue:
112
Sequence:
MDGEEKTYGGCEGPDAMYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEVNFREIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC
  
Inhibitor
Name:
BDBM50446138
Synonyms:
CHEMBL3108881
Type:
Small organic molecule
Emp. Form.:
C21H22N4O5
Mol. Mass.:
410.4232
SMILES:
Cc1cc(CC(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2cnco2)on1 |r|
Structure:
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