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Target
Elongin-C
Ligand
BDBM50014097
Substrate
n/a
Meas. Tech.
ChEMBL_1350286 (CHEMBL3267624)
IC50
900±n/a nM
Citation
 Guo, W; Wisniewski, JA; Ji, H Hot spot-based design of small-molecule inhibitors for protein-protein interactions. Bioorg Med Chem Lett 24:2546-54 (2014) [PubMed]  Article 
Target
Name:
Elongin-C
Synonyms:
ELOC | ELOC_HUMAN | Elongin 15 kDa subunit | Elongin-C | RNA polymerase II transcription factor SIII subunit C | SIII p15 | TCEB1 | Transcription elongation factor B polypeptide 1
Type:
PROTEIN
Mol. Mass.:
12466.49
Organism:
Homo sapiens (Human)
Description:
ChEMBL_108414
Residue:
112
Sequence:
MDGEEKTYGGCEGPDAMYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEVNFREIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC
  
Inhibitor
Name:
BDBM50014097
Synonyms:
CHEMBL3260851
Type:
Small organic molecule
Emp. Form.:
C24H26N4O3S
Mol. Mass.:
450.553
SMILES:
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)c2cccc(N)c2C)cc1 |r|
Structure:
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