Reaction Details Report a problem with these data
Target
C-C motif chemokine 5
Ligand
BDBM50017347
Substrate
n/a
Meas. Tech.
ChEMBL_1363187 (CHEMBL3293902)
Kd
25000000±n/a nM
Citation
 Roy, S; El Hadri, A; Richard, S; Denis, F; Holte, K; Duffner, J; Yu, F; Galcheva-Gargova, Z; Capila, I; Schultes, B; Petitou, M; Kaundinya, GV Synthesis and biological evaluation of a unique heparin mimetic hexasaccharide for structure-activity relationship studies. J Med Chem 57:4511-20 (2014) [PubMed]  Article 
Target
Name:
C-C motif chemokine 5
Synonyms:
CCL5 | CCL5_HUMAN | D17S136E | EoCP | Eosinophil chemotactic cytokine | RANTES(3-68) | RANTES(4-68) | SCYA5 | SIS-delta | Small-inducible cytokine A5 | T cell-specific protein P228 | T-cell-specific protein RANTES | TCP228
Type:
PROTEIN
Mol. Mass.:
9996.11
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1363187
Residue:
91
Sequence:
MKVSAAALAVILIATALCAPASASPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNPAVVFVTRKNRQVCANPEKKWVREYINSLEMS
  
Inhibitor
Name:
BDBM50017347
Synonyms:
CHEMBL3288259
Type:
Small organic molecule
Emp. Form.:
C41H61N4Na9O49S6
Mol. Mass.:
1793.218
SMILES:
[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[H][C@]1(O[C@@H]2O[C@H]([C@@H](O)[C@H](O)[C@H]2OS([O-])(=O)=O)C([O-])=O)[C@H](O)[C@@H](NS([O-])(=O)=O)[C@@H](O[C@@]2([H])[C@H](O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@@]3([H])[C@H](O)[C@@H](NS([O-])(=O)=O)[C@@H](O[C@@]4([H])[C@H](O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@@]5([H])[C@H](O)[C@@H](NS([O-])(=O)=O)[C@@H](OCCCCCN)O[C@@H]5CO)O[C@H]4C([O-])=O)O[C@@H]3CO)O[C@H]2C([O-])=O)O[C@@H]1CO |r|
Structure:
Search PDB for entries with ligand similarity: