Reaction Details Report a problem with these data
Target
D(1A) dopamine receptor
Ligand
BDBM50384969
Substrate
n/a
Meas. Tech.
ChEMBL_1365235 (CHEMBL3292985)
Ki
1897±n/a nM
Citation
 Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY Identification of a new selective dopamine D4 receptor ligand. Bioorg Med Chem 22:3105-14 (2014) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50384969
Synonyms:
CHEMBL2037431
Type:
Small organic molecule
Emp. Form.:
C21H24ClN3S
Mol. Mass.:
385.953
SMILES:
Clc1ccc(cc1)N1CCN(CCCCc2nc3ccccc3s2)CC1
Structure:
Search PDB for entries with ligand similarity: