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Target
DNA polymerase beta
Ligand
BDBM50020676
Substrate
n/a
Meas. Tech.
ChEMBL_1361926 (CHEMBL3293530)
IC50
30800±n/a nM
Citation
 Le, DH; Takenaka, Y; Hamada, N; Mizushina, Y; Tanahashi, T Polyketides from the cultured lichen mycobiont of a Vietnamese Pyrenula sp. J Nat Prod 77:1404-12 (2014) [PubMed]  Article 
Target
Name:
DNA polymerase beta
Synonyms:
DNA Polymerase beta | DPOLB_RAT | Polb
Type:
PROTEIN
Mol. Mass.:
38334.34
Organism:
Rattus norvegicus
Description:
ChEMBL_1361926
Residue:
335
Sequence:
MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIKTLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGSFRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQLPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
  
Inhibitor
Name:
BDBM50020676
Synonyms:
CHEBI:41846 | CHEMBL566812
Type:
Small organic molecule
Emp. Form.:
C10H17N2O13P3
Mol. Mass.:
466.1689
SMILES:
Cc1cn([C@H]2CC[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)c(=O)[nH]c1=O |r|
Structure:
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