Reaction Details Report a problem with these data
Target
Chymotrypsinogen A
Ligand
BDBM50021352
Substrate
n/a
Meas. Tech.
ChEMBL_1366692 (CHEMBL3296843)
Ki
290±n/a nM
Citation
 Troiano, V; Scarbaci, K; Ettari, R; Micale, N; Cerchia, C; Pinto, A; Schirmeister, T; Novellino, E; Grasso, S; Lavecchia, A; Zappalą, M Optimization of peptidomimetic boronates bearing a P3 bicyclic scaffold as proteasome inhibitors. Eur J Med Chem 83:1-14 (2014) [PubMed]  Article 
Target
Name:
Chymotrypsinogen A
Synonyms:
Alpha-chymotrypsin | CTRA_BOVIN | Chymotrypsin A | Chymotrypsin A chain A | Chymotrypsin A chain B | Chymotrypsin A chain C | Chymotrypsinogen A | alpha-Chymotrypsin (α-Chymotrypsin)
Type:
Serine protease
Mol. Mass.:
25670.88
Organism:
Bos taurus (bovine)
Description:
n/a
Residue:
245
Sequence:
CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTLAAN
  
Inhibitor
Name:
BDBM50021352
Synonyms:
CHEMBL3287943
Type:
Small organic molecule
Emp. Form.:
C16H20BBrN2O4
Mol. Mass.:
395.056
SMILES:
CC(C)C[C@H](NC(=O)Cn1ccc2ccc(Br)cc2c1=O)B(O)O |r|
Structure:
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