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Target
Dual specificity protein kinase CLK1
Ligand
BDBM50021616
Substrate
n/a
Meas. Tech.
ChEMBL_1367648 (CHEMBL3299299)
IC50
210±n/a nM
Citation
 Beniddir, MA; Le Borgne, E; Iorga, BI; Loaëc, N; Lozach, O; Meijer, L; Awang, K; Litaudon, M Acridone alkaloids from Glycosmis chlorosperma as DYRK1A inhibitors. J Nat Prod 77:1117-22 (2014) [PubMed]  Article 
Target
Name:
Dual specificity protein kinase CLK1
Synonyms:
CDC-like kinase 1 | CLK1_MOUSE | Clk | Clk1 | Protein kinase STY | Sty
Type:
PROTEIN
Mol. Mass.:
57124.52
Organism:
Mus musculus
Description:
ChEMBL_1502245
Residue:
483
Sequence:
MRHSKRTYCPDWDERDWDYGTWRSSSSHKRKKRSHSSAREQKRCRYDHSKTTDSYYLESRSINEKAYHSRRYVDEYRNDYMGYEPGHPYGEPGSRYQMHSSKSSGRSGRSSYKSKHRSRHHTSQHHSHGKSHRRKRSRSVEDDEEGHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKVGGRRVAVKIVKNVDRYCEAAQSEIQVLEHLNTTDPHSTFRCVQMLEWFEHRGHICIVFELLGLSTYDFIKENSFLPFRMDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVKSDYTEAYNPKMKRDERTIVNPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSREHLAMMERILGPLPKHMIQKTRKRRYFHHDRLDWDEHSSAGRYVSRRCKPLKEFMLSQDAEHELLFDLIGKMLEYDPAKRITLKEALKHPFFYPLKKHT
  
Inhibitor
Name:
BDBM50021616
Synonyms:
CHEMBL3297832
Type:
Small organic molecule
Emp. Form.:
C19H17NO5
Mol. Mass.:
339.342
SMILES:
COc1c(O)ccc2c1[nH]c1c3C=CC(C)(C)Oc3cc(O)c1c2=O |c:13|
Structure:
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