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TargetMatrix metalloproteinase-7 (MMP7)
LigandBDBM50028945
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1432369
Ki 79±n/a nM
Citation Fabre, BRamos, Ade Pascual-Teresa, B Targeting matrix metalloproteinases: exploring the dynamics of the s1' pocket in the design of selective, small molecule inhibitors. J Med Chem57:10205-19 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Matrix metalloproteinase-7 (MMP7)
Name:Matrix metalloproteinase 7
Synonyms:Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7)
Type:Enzyme
Mol. Mass.:29681.54
Organism:Homo sapiens (Human)
Description:P09237
Residue:267
Sequence:
MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK
EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL
PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF
APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD
PQNFKLSQDDIKGIQKLYGKRSNSRKK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50028945
NameBDBM50028945
Synonyms:CHEMBL1738911
TypeSmall organic molecule
Emp. Form.C19H25BrN6O4S
Mol. Mass.513.409
SMILESON(C=O)[C@@H](CCCc1ncccn1)CS(=O)(=O)N1CCN(CC1)c1ccc(Br)cn1 |r|
Structure
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