Reaction Details Report a problem with these data
Target
Glutathione S-transferase P
Ligand
BDBM50038306
Substrate
n/a
Meas. Tech.
ChEMBL_1441152 (CHEMBL3378816)
IC50
100±n/a nM
Citation
 Rotili, D; De Luca, A; Tarantino, D; Pezzola, S; Forgione, M; Morozzo Della Rocca, B; Falconi, M; Mai, A; Caccuri, AM Synthesis and structure--activity relationship of new cytotoxic agents targeting human glutathione-S-transferases. Eur J Med Chem 89:156-71 (2014) [PubMed]  Article 
Target
Name:
Glutathione S-transferase P
Synonyms:
FAEES3 | GST class-pi | GST3 | GSTP1 | GSTP1-1 | GSTP1_HUMAN | Glutathione S-transferase | Glutathione S-transferase (GST) | Glutathione S-transferase P | Glutathione S-transferase Pi | Glutathione transferase (GST)
Type:
Enzyme
Mol. Mass.:
23353.53
Organism:
Homo sapiens (Human)
Description:
P09211
Residue:
210
Sequence:
MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ
  
Inhibitor
Name:
BDBM50038306
Synonyms:
CHEMBL3360520
Type:
Small organic molecule
Emp. Form.:
C22H18N4O5S
Mol. Mass.:
450.467
SMILES:
[O-][N+](=O)c1ccc(Sc2ccc(CCC(=O)NOCc3ccccc3)cc2)c2nonc12
Structure:
Search PDB for entries with ligand similarity: