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Target
Protein tyrosine phosphatase type IVA 2
Ligand
BDBM50059141
Substrate
n/a
Meas. Tech.
ChEMBL_1461023 (CHEMBL3395081)
IC50
69400±n/a nM
Citation
 Hoeger, B; Diether, M; Ballester, PJ; Köhn, M Biochemical evaluation of virtual screening methods reveals a cell-active inhibitor of the cancer-promoting phosphatases of regenerating liver. Eur J Med Chem 88:89-100 (2014) [PubMed]  Article 
Target
Name:
Protein tyrosine phosphatase type IVA 2
Synonyms:
PRL2 | PTP4A2 | PTPCAAX2 | TP4A2_HUMAN
Type:
PROTEIN
Mol. Mass.:
19133.04
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1461023
Residue:
167
Sequence:
MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGHCCVQ
  
Inhibitor
Name:
BDBM50059141
Synonyms:
CHEMBL3393149
Type:
Small organic molecule
Emp. Form.:
C14H14BrNO4
Mol. Mass.:
340.169
SMILES:
COc1cc(\C=C(/C#N)C(=O)OC(C)C)cc(Br)c1O
Structure:
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