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Target
Protein tyrosine phosphatase type IVA 2
Ligand
BDBM50059085
Substrate
n/a
Meas. Tech.
ChEMBL_1461023 (CHEMBL3395081)
IC50
188000±n/a nM
Citation
 Hoeger, B; Diether, M; Ballester, PJ; Köhn, M Biochemical evaluation of virtual screening methods reveals a cell-active inhibitor of the cancer-promoting phosphatases of regenerating liver. Eur J Med Chem 88:89-100 (2014) [PubMed]  Article 
Target
Name:
Protein tyrosine phosphatase type IVA 2
Synonyms:
PRL2 | PTP4A2 | PTPCAAX2 | TP4A2_HUMAN
Type:
PROTEIN
Mol. Mass.:
19133.04
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1461023
Residue:
167
Sequence:
MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGHCCVQ
  
Inhibitor
Name:
BDBM50059085
Synonyms:
CHEBI:8830 | Rhodanine
Type:
Small organic molecule
Emp. Form.:
C3H3NOS2
Mol. Mass.:
133.192
SMILES:
O=C1CSC(=S)N1
Structure:
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