Reaction Details Report a problem with these data
Target
Fibroblast growth factor 2
Ligand
BDBM50063843
Substrate
n/a
Meas. Tech.
ChEMBL_1462508 (CHEMBL3398981)
Kd
23±n/a nM
Citation
 Wakao, M; Obata, R; Miyachi, K; Kaitsubata, Y; Kondo, T; Sakami, C; Suda, Y Synthesis of a chondroitin sulfate disaccharide library and a GAG-binding protein interaction analysis. Bioorg Med Chem Lett 25:1407-11 (2015) [PubMed]  Article 
Target
Name:
Fibroblast growth factor 2
Synonyms:
Basic fibroblast growth factor | FGF-2 | FGF2 | FGF2_HUMAN | FGFB | Fibroblast growth factor 2 (bFGF) | Fibroblast growth factor receptor 2 (FGF-2) | HBGF-2 | Heparin-binding growth factor 2
Type:
Protein
Mol. Mass.:
30803.89
Organism:
Homo sapiens (Human)
Description:
P09038
Residue:
288
Sequence:
MVGVGGGDVEDVTPRPGGCQISGRGARGCNGIPGAAAWEAALPRRRPRRHPSVNPRSRAAGSPRTRGRRTEERPSGSRLGDRGRGRALPGGRLGGRGRGRAPERVGGRGRGRGTAAPRAAPAARGSRPGPAGTMAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
  
Inhibitor
Name:
BDBM50063843
Synonyms:
CHEMBL3397491
Type:
Small organic molecule
Emp. Form.:
C34H50N3Na3O23S4
Mol. Mass.:
1065.996
SMILES:
[Na+].[Na+].[Na+].[H][C@@]1(O[C@H]2[C@@H](O)[C@@H](COS([O-])(=O)=O)O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc3cccc(NC(=O)CCCCC4CCSS4)c3)[C@@H]2NC(C)=O)O[C@@H]([C@@H](O)[C@H](O)[C@H]1OS([O-])(=O)=O)C([O-])=O |r|
Structure:
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