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Target
Interleukin-5
Ligand
BDBM50068121
Substrate
n/a
Meas. Tech.
ChEMBL_1464308 (CHEMBL3404575)
IC50
6100±n/a nM
Citation
 Venkateswararao, E; Manickam, M; Boggu, P; Kim, Y; Jung, SH Exploration of benzamidochromenone derivatives with conformational restrictor as interleukin-5 inhibitors. Bioorg Med Chem 23:2498-504 (2015) [PubMed]  Article 
Target
Name:
Interleukin-5
Synonyms:
IL5_MOUSE | Il-5 | Il5
Type:
PROTEIN
Mol. Mass.:
15414.97
Organism:
Mus musculus
Description:
ChEMBL_1464308
Residue:
133
Sequence:
MRRMLLHLSVLTLSCVWATAMEIPMSTVVKETLTQLSAHRALLTSNETMRLPVPTHKNHQLCIGEIFQGLDILKNQTVRGGTVEMLFQNLSLIKKYIDRQKEKCGEERRRTRQFLDYLQEFLGVMSTEWAMEG
  
Inhibitor
Name:
BDBM50068121
Synonyms:
CHEMBL3402258
Type:
Small organic molecule
Emp. Form.:
C25H25NO5
Mol. Mass.:
419.4697
SMILES:
CC(=O)OCc1c(oc2ccc(NC(=O)c3ccccc3)cc2c1=O)C1CCCCC1
Structure:
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