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TargetKrueppel-like factor 10
LigandBDBM50366567
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1467056
IC50 100000±n/a nM
Citation Khedkar, SASun, XRigby, ACFeinberg, MW Discovery of small molecule inhibitors to Krüppel-like factor 10 (KLF10): implications for modulation of T regulatory cell differentiation. J Med Chem58:1466-78 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Krueppel-like factor 10
Name:Krueppel-like factor 10
Synonyms:EGR-alpha | KLF10 | Krueppel-like factor 10 | TGFB-inducible early growth response protein 1 | TIEG | TIEG-1 | TIEG1 | Transforming growth factor-beta-inducible early growth response protein 1
Type:PROTEIN
Mol. Mass.:52579.81
Organism:Homo sapiens (Human)
Description:ChEMBL_109571
Residue:480
Sequence:
MLNFGASLQQTAEERMEMISERPKESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKKYV
ENRPVTPVSDLSEEENLLPGTPDFHTIPAFCLTPPYSPSDFEPSQVSNLMAPAPSTVHFK
SLSDTAKPHIAAPFKEEEKSPVSAPKLPKAQATSVIRHTADAQLCNHQTCPMKAASILNY
QNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCERNTVADVDEKASAALYDFSVPSSETVI
CRSQPAPVSPQQKSVLVSPPAVSAGGVPPMPVICQMVPLPANNPVVTTVVPSTPPSQPPA
VCPPVVFMGTQVPKGAVMFVVPQPVVQSSKPPVVSPNGTRLSPIAPAPGFSPSAAKVTPQ
IDSSRIRSHICSHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHR
RTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50366567
NameBDBM50366567
Synonyms:ATOMOXETINE
TypeSmall organic molecule
Emp. Form.C17H21NO
Mol. Mass.255.3547
SMILESCNCC[C@@H](Oc1ccccc1C)c1ccccc1 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a