Reaction Details Report a problem with these data
Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50073397
Substrate
n/a
Meas. Tech.
ChEMBL_1469668 (CHEMBL3413067)
IC50
1020±n/a nM
Citation
 Wang, SF; Yin, Y; Zhang, YL; Mi, SW; Zhao, MY; Lv, PC; Wang, BZ; Zhu, HL Synthesis, biological evaluation and 3D-QSAR studies of novel 5-phenyl-1H-pyrazol cinnamamide derivatives as novel antitubulin agents. Eur J Med Chem 93:291-9 (2015) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50073397
Synonyms:
CHEMBL3408700
Type:
Small organic molecule
Emp. Form.:
C19H13BrF3N3O
Mol. Mass.:
436.225
SMILES:
FC(F)(F)c1ccc(\C=C\C(=O)Nc2cc([nH]n2)-c2ccc(Br)cc2)cc1
Structure:
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