Reaction Details Report a problem with these data
Target
Macrophage migration inhibitory factor
Ligand
BDBM50240520
Substrate
n/a
Meas. Tech.
ChEMBL_1467648 (CHEMBL3411010)
IC50
530±n/a nM
Citation
Spencer, ES; Dale, EJ; Gommans, AL; Rutledge, MT; Vo, CT; Nakatani, Y; Gamble, AB; Smith, RA; Wilbanks, SM; Hampton, MB; Tyndall, JD Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor. Eur J Med Chem 93:501-10 (2015) [PubMed] Article
More Info.:
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:
Enzyme
Mol. Mass.:
12478.18
Organism:
Homo sapiens (Human)
Description:
P14174
Residue:
115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA