Reaction Details Report a problem with these data
Target
Fibroblast growth factor 2
Ligand
BDBM50073747
Substrate
n/a
Meas. Tech.
ChEMBL_1467830 (CHEMBL3412555)
Kd
5.2±n/a nM
Citation
 Miyachi, K; Wakao, M; Suda, Y Syntheses of chondroitin sulfate tetrasaccharide structures containing 4,6-disulfate patterns and analysis of their interaction with glycosaminoglycan-binding protein. Bioorg Med Chem Lett 25:1552-5 (2015) [PubMed]  Article 
Target
Name:
Fibroblast growth factor 2
Synonyms:
Basic fibroblast growth factor | FGF-2 | FGF2 | FGF2_HUMAN | FGFB | Fibroblast growth factor 2 (bFGF) | Fibroblast growth factor receptor 2 (FGF-2) | HBGF-2 | Heparin-binding growth factor 2
Type:
Protein
Mol. Mass.:
30803.89
Organism:
Homo sapiens (Human)
Description:
P09038
Residue:
288
Sequence:
MVGVGGGDVEDVTPRPGGCQISGRGARGCNGIPGAAAWEAALPRRRPRRHPSVNPRSRAAGSPRTRGRRTEERPSGSRLGDRGRGRALPGGRLGGRGRGRAPERVGGRGRGRGTAAPRAAPAARGSRPGPAGTMAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
  
Inhibitor
Name:
BDBM50073747
Synonyms:
CHEMBL3409457
Type:
Small organic molecule
Emp. Form.:
C48H70N4Na4O40S6
Mol. Mass.:
1627.421
SMILES:
[Na+].[Na+].[Na+].[Na+].[H][C@@]1(O[C@H]2[C@@H](OS([O-])(=O)=O)[C@@H](COS([O-])(=O)=O)O[C@@]([H])(O[C@H]3[C@H](O)[C@@H](O)[C@]([H])(O[C@@H]4[C@@H](NC(C)=O)[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc5cccc(NC(=O)CCCCC6CCSS6)c5)O[C@H](COS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)O[C@@H]3C(O)=O)[C@@H]2NC(C)=O)O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O |r|
Structure:
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