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Target
Oligo-1,6-glucosidase IMA1
Ligand
BDBM50073946
Substrate
n/a
Meas. Tech.
ChEMBL_1467867 (CHEMBL3412764)
IC50
<50000±n/a nM
Citation
 Niaz, H; Kashtoh, H; Khan, JA; Khan, A; Wahab, AT; Alam, MT; Khan, KM; Perveen, S; Choudhary, MI Synthesis of diethyl 4-substituted-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates as a new series of inhibitors against yeasta-glucosidase. Eur J Med Chem 95:199-209 (2015) [PubMed]  Article 
Target
Name:
Oligo-1,6-glucosidase IMA1
Synonyms:
α-glucosidase | Alpha-glucosidase | Alpha-glucosidase (α-glucosidase) | IMA1 | MALX3_YEAST | Oligo-1,6-glucosidase
Type:
Protein
Mol. Mass.:
68577.59
Organism:
Saccharomyces cerevisiae S288c (Baker's yeast)
Description:
n/a
Residue:
589
Sequence:
MTISSAHPETEPKWWKEATFYQIYPASFKDSNDDGWGDMKGIASKLEYIKELGADAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVVGLPDAPVVDKNSTWQSSDPYTLNGPRIHEFHQEMNQFIRNRVKDGREIMTVGEMQHASDETKRLYTSASRHELSELFNFSHTDVGTSPLFRYNLVPFELKDWKIALAELFRYINGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLSALTGTLYVYQGQELGQINFKNWPVEKYEDVEIRNNYNAIKEEHGENSEEMKKFLEAIALISRDHARTPMQWSREEPNAGFSGPSAKPWFYLNDSFREGINVEDEIKDPNSVLNFWKEALKFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYNNKTLFAALNFSSDATDFKIPNDDSSFKLEFGNYPKKEVDASSRTLKPWEGRIYISE
  
Inhibitor
Name:
BDBM50073946
Synonyms:
CHEBI:83605 | CHEMBL3409638
Type:
Small organic molecule
Emp. Form.:
C14H21NO4
Mol. Mass.:
267.3208
SMILES:
CCOC(=O)C1=C(C)NC(C)=C(C1C)C(=O)OCC |c:5,10|
Structure:
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