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Target
Integrin-linked protein kinase
Ligand
BDBM50078259
Substrate
n/a
Meas. Tech.
ChEMBL_1470576 (CHEMBL3419802)
Kd
8700±n/a nM
Citation
 Yan, R; Chuang, HC; Kapuriya, N; Chou, CC; Lai, PT; Chang, HW; Yang, CN; Kulp, SK; Chen, CS Exploitation of the ability of¿-tocopherol to facilitate membrane co-localization of Akt and PHLPP1 to develop PHLPP1-targeted Akt inhibitors. J Med Chem 58:2290-8 (2015) [PubMed]  Article 
Target
Name:
Integrin-linked protein kinase
Synonyms:
ILK | ILK1 | ILK2 | ILK_HUMAN | Integrin-linked protein kinase (ILK) | Serine/threonine-protein kinase ILK-1
Type:
Protein
Mol. Mass.:
51429.75
Organism:
Homo sapiens (Human)
Description:
Q13418
Residue:
452
Sequence:
MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNGTLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALDMARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQDK
  
Inhibitor
Name:
BDBM50078259
Synonyms:
CHEMBL3414669
Type:
Small organic molecule
Emp. Form.:
C18H28O2
Mol. Mass.:
276.4137
SMILES:
CC(C)CCC[C@]1(C)CCc2cc(O)c(C)c(C)c2O1 |r|
Structure:
Search PDB for entries with ligand similarity: