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Target
Macrophage-expressed gene 1 protein
Ligand
BDBM50078882
Substrate
n/a
Meas. Tech.
ChEMBL_1472482 (CHEMBL3420871)
IC50
2100±n/a nM
Citation
 Filosa, R; Peduto, A; Schaible, AM; Krauth, V; Weinigel, C; Barz, D; Petronzi, C; Bruno, F; Roviezzo, F; Spaziano, G; D'Agostino, B; De Rosa, M; Werz, O Novel series of benzoquinones with high potency against 5-lipoxygenase in human polymorphonuclear leukocytes. Eur J Med Chem 94:132-9 (2015) [PubMed]  Article 
Target
Name:
Macrophage-expressed gene 1 protein
Synonyms:
MPEG1 | MPEG1_HUMAN | Macrophage gene 1 protein | Macrophage-expressed gene 1 protein | Mpg-1
Type:
PROTEIN
Mol. Mass.:
78593.74
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109592
Residue:
716
Sequence:
MNNFRATILFWAAAAWAKSGKPSGEMDEVGVQKCKNALKLPVLEVLPGGGWDNLRNVDMGRVMELTYSNCRTTEDGQYIIPDEIFTIPQKQSNLEMNSEILESWANYQSSTSYSINTELSLFSKVNGKFSTEFQRMKTLQVKDQAITTRVQVRNLVYTVKINPTLELSSGFRKELLDISDRLENNQTRMATYLAELLVLNYGTHVTTSVDAGAALIQEDHLRASFLQDSQSSRSAVTASAGLAFQNTVNFKFEENYTSQNVLTKSYLSNRTNSRVQSIGGVPFYPGITLQAWQQGITNHLVAIDRSGLPLHFFINPNMLPDLPGPLVKKVSKTVETAVKRYYTFNTYPGCTDLNSPNFNFQANTDDGSCEGKMTNFSFGGVYQECTQLSGNRDVLLCQKLEQKNPLTGDFSCPSGYSPVHLLSQIHEEGYNHLECHRKCTLLVFCKTVCEDVFQVAKAEFRAFWCVASSQVPENSGLLFGGLFSSKSINPMTNAQSCPAGYFPLRLFENLKVCVSQDYELGSRFAVPFGGFFSCTVGNPLVDPAISRDLGAPSLKKCPGGFSQHPALISDGCQVSYCVKSGLFTGGSLPPARLPPFTRPPLMSQAATNTVIVTNSENARSWIKDSQTHQWRLGEPIELRRAMNVIHGDGGGLSGGAAAGVTVGVTTILAVVITLAIYGTRKFKKKAYQAIEERQSLVPGTAATGDTTYQEQGQSPA
  
Inhibitor
Name:
BDBM50078882
Synonyms:
CHEMBL462998
Type:
Small organic molecule
Emp. Form.:
C21H34O4
Mol. Mass.:
350.4923
SMILES:
CCCCCCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O |c:15,t:20|
Structure:
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