Reaction Details Report a problem with these data
Target
Somatostatin receptor type 4
Ligand
BDBM50081055
Substrate
n/a
Meas. Tech.
ChEMBL_1475512 (CHEMBL3424505)
EC50
0.400000±n/a nM
Citation
 Abdel-Magid, AF Treating pain with somatostatin receptor subtype 4 agonists. ACS Med Chem Lett 6:110-1 (2015) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 4
Synonyms:
SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4)
Type:
Enzyme
Mol. Mass.:
42015.38
Organism:
Homo sapiens (Human)
Description:
P31391
Residue:
388
Sequence:
MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
  
Inhibitor
Name:
BDBM50081055
Synonyms:
CHEMBL3421843 | US10166214, Example 49 | US10675268, Example 49 | US9789082, Example 49
Type:
Small organic molecule
Emp. Form.:
C17H22N4O
Mol. Mass.:
298.3828
SMILES:
[H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nn(C)c2ccccc12 |r|
Structure:
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