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TargetUTS2R
LigandBDBM50089670
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1496212
EC50 12±n/a nM
Citation Dufour-Gallant, JChatenet, DLubell, WD De Novo Conception of Small Molecule Modulators Based on Endogenous Peptide Ligands: Pyrrolodiazepin-2-oneż-Turn Mimics That Differentially Modulate Urotensin II Receptor-Mediated Vasoconstriction ex Vivo. J Med Chem58:4624-37 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
UTS2R
Name:UTS2R
Synonyms:G-protein coupled receptor 14 | G-protein coupled sensory epithelial neuropeptide-like receptor | SENR | UR-II-R | Urotensin-II
Type:Enzyme Catalytic Domain
Mol. Mass.:42725.34
Organism:RAT
Description:Urotensin-II UTS2R RAT::P49684
Residue:386
Sequence:
MALSLESTTSFHMLTVSGSTVTELPGDSNVSLNSSWSGPTDPSSLKDLVATGVIGAVLSA
MGVVGMVGNVYTLVVMCRFLRASASMYVYVVNLALADLLYLLSIPFIIATYVTKDWHFGD
VGCRVLFSLDFLTMHASIFTLTIMSSERYAAVLRPLDTVQRSKGYRKLLVLGTWLLALLL
TLPMMLAIQLVRRGSKSLCLPAWGPRAHRTYLTLLFGTSIVGPGLVIGLLYVRLARAYWL
SQQASFKQTRRLPNPRVLYLILGIVLLFWACFLPFWLWQLLAQYHEAMPLTPETARIVNY
LTTCLTYGNSCINPFLYTLLTKNYREYLRGRQRSLGSSCHSPGSPGSFLPSRVHLQQDSG
RSLSSSSQQATETLMLSPVPRNGALL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50089670
NameBDBM50089670
Synonyms:CHEMBL3577301
TypeSmall organic molecule
Emp. Form.C29H28N4O4
Mol. Mass.496.557
SMILESNCCC[C@@H]1N=C(c2[nH]c(cc2N(CCc2ccc(O)cc2)C1=O)C(O)=O)c1cccc2ccccc12 |r,c:5|
Structure
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