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TargetProgrammed cell death 1 ligand 1
LigandBDBM50091333
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1497759
IC50 11±n/a nM
Citation Abdel-Magid, AF Inhibitors of the PD-1/PD-L1 Pathway Can Mobilize the Immune System: An Innovative Potential Therapy for Cancer and Chronic Infections. ACS Med Chem Lett6:489-90 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Programmed cell death 1 ligand 1
Name:Programmed cell death 1 ligand 1
Synonyms:B7 homolog 1 | B7-H1 | B7H1 | CD274 | CD_antigen=CD274 | PD-L1 | PDCD1 ligand 1 | PDCD1L1 | PDCD1LG1 | PDL1 | Programmed cell death 1 ligand 1 | Programmed death ligand 1
Type:PROTEIN
Mol. Mass.:33278.49
Organism:Homo sapiens
Description:ChEMBL_109807
Residue:290
Sequence:
MRIFAVFIFMTYWHLLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEME
DKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGG
ADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTT
TTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTH
LVILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNSKKQSDTHLEET
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  Blast E-value cutoff:
BDBM50091333
NameBDBM50091333
Synonyms:CHEMBL3582253
TypeSmall organic molecule
Emp. Form.C30H36N2O3
Mol. Mass.472.6184
SMILESCc1cc(CN2CCC(CC2)C(=O)NCCO)ccc1OCc1cccc(c1C)-c1ccccc1
Structure
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