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Target
Metallo-beta-lactamase L1 type 3
Ligand
BDBM50092842
Substrate
n/a
Meas. Tech.
ChEMBL_1500319 (CHEMBL3588630)
Ki
280±n/a nM
Citation
 Liu, XL; Shi, Y; Kang, JS; Oelschlaeger, P; Yang, KW Amino Acid Thioester Derivatives: A Highly Promising Scaffold for the Development of Metallo-ß-lactamase L1 Inhibitors. ACS Med Chem Lett 6:660-4 (2015) [PubMed]  Article 
Target
Name:
Metallo-beta-lactamase L1 type 3
Synonyms:
BLA1_STEMA | Beta-lactamase L1
Type:
PROTEIN
Mol. Mass.:
30803.13
Organism:
Stenotrophomonas maltophilia
Description:
ChEMBL_1500319
Residue:
290
Sequence:
MRSTLLAFALAVALPAAHTSAAEVPLPQLRAYTVDASWLQPMAPLQIADHTWQIGTEDLTALLVQTPDGAVLLDGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRRTGAKVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVFTAHFMAGHTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHLIEDYRRSFATVRALPCDVLLTPHPGASNWDYAAGARAGAKALTCKAYADAAEQKFDGQLAKETAGAR
  
Inhibitor
Name:
BDBM50092842
Synonyms:
CHEMBL3586476
Type:
Small organic molecule
Emp. Form.:
C13H17NO4S2
Mol. Mass.:
315.408
SMILES:
CC(C)[C@H](NC(=O)Cc1cccs1)C(=O)SCC(O)=O |r|
Structure:
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