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Target
Metallo-beta-lactamase L1 type 3
Ligand
BDBM50092997
Substrate
n/a
Meas. Tech.
ChEMBL_1500319 (CHEMBL3588630)
Ki
190±n/a nM
Citation
 Liu, XL; Shi, Y; Kang, JS; Oelschlaeger, P; Yang, KW Amino Acid Thioester Derivatives: A Highly Promising Scaffold for the Development of Metallo-ß-lactamase L1 Inhibitors. ACS Med Chem Lett 6:660-4 (2015) [PubMed]  Article 
Target
Name:
Metallo-beta-lactamase L1 type 3
Synonyms:
BLA1_STEMA | Beta-lactamase L1
Type:
PROTEIN
Mol. Mass.:
30803.13
Organism:
Stenotrophomonas maltophilia
Description:
ChEMBL_1500319
Residue:
290
Sequence:
MRSTLLAFALAVALPAAHTSAAEVPLPQLRAYTVDASWLQPMAPLQIADHTWQIGTEDLTALLVQTPDGAVLLDGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRRTGAKVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVFTAHFMAGHTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHLIEDYRRSFATVRALPCDVLLTPHPGASNWDYAAGARAGAKALTCKAYADAAEQKFDGQLAKETAGAR
  
Inhibitor
Name:
BDBM50092997
Synonyms:
CHEMBL3586481
Type:
Small organic molecule
Emp. Form.:
C20H24N2O5S3
Mol. Mass.:
468.61
SMILES:
OC(=O)CSC(=O)[C@H](CCCCNC(=O)Cc1cccs1)NC(=O)Cc1cccs1 |r|
Structure:
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