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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50093709
Substrate
n/a
Meas. Tech.
ChEMBL_1501478 (CHEMBL3586840)
IC50
420000±n/a nM
Citation
 Khattab, SN; Haiba, NS; Asal, AM; Bekhit, AA; Amer, A; Abdel-Rahman, HM; El-Faham, A Synthesis and evaluation of quinazoline amino acid derivatives as mono amine oxidase (MAO) inhibitors. Bioorg Med Chem 23:3574-85 (2015) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_BOVIN | Amine oxidase [flavin-containing] B | MAO-B | MAOB | Monoamine Oxidase Type B (MAO-B) | Monoamine oxidase | Monoamine oxidase B | Monoamine oxidase type B
Type:
PROTEIN
Mol. Mass.:
58428.94
Organism:
Bos taurus
Description:
ChEMBL_1501478
Residue:
520
Sequence:
MSSKCDVVVVGGGISGMAAAKLLHDSGLNVIVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNHILRLSKELGLETYKVNEVERLIHHTKGKSYPFRGSFPSVWNPITYLDHNNLWRTMDDMGREIPSDAPWKAPLAEQWDLMTMKELLDKICWTESSKQLAILFVNLCVTAEIHEVSALWFLWYVKQCGGTTRIFSTSNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIHIDQTGENVLVETLNHELYEAKYVISAVPPVLGMKIHFNPPLPMMRNQLITRVPLGSVIKSIVYYKEPFWRNMDYCGSMIIEGEEAPVAYALDDTKPDGSYPAIIGFILAHKARKLARLTKEERLKKLCDLYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTSYFPPGIMTQYGRVLRQPVGRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWLPEPESVDVPAKPITTTFLQRHLPSVPGLLKLIGLTTIFSATALGFLAHKRGLLVRI
  
Inhibitor
Name:
BDBM50093709
Synonyms:
CHEMBL3585840
Type:
Small organic molecule
Emp. Form.:
C17H17ClN4O2
Mol. Mass.:
344.795
SMILES:
NNC(=O)CCN1C(Nc2ccccc2C1=O)c1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: