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Target
Growth hormone secretagogue receptor type 1
Ligand
BDBM50096215
Substrate
n/a
Meas. Tech.
ChEMBL_1505782 (CHEMBL3595020)
IC50
13±n/a nM
Citation
 Takahashi, B; Funami, H; Iwaki, T; Maruoka, H; Shibata, M; Koyama, M; Nagahira, A; Kamiide, Y; Kanki, S; Igawa, Y; Muto, T Orally active ghrelin receptor inverse agonists and their actions on a rat obesity model. Bioorg Med Chem 23:4792-803 (2015) [PubMed]  Article 
Target
Name:
Growth hormone secretagogue receptor type 1
Synonyms:
GH-releasing peptide receptor | GHRP | GHS-R | GHSR_RAT | Ghrelin receptor | Ghsr | Growth hormone secretagogue receptor type 1
Type:
PROTEIN
Mol. Mass.:
40970.19
Organism:
Rattus norvegicus
Description:
ChEMBL_11556
Residue:
364
Sequence:
MWNATPSEEPEPNVTLDLDWDASPGNDSLPDELLPLFPAPLLAGVTATCVALFVVGISGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVILVIWAVAFCSAGPIFVLVGVEHENGTDPRDTNECRATEFAVRSGLLTVMVWVSSVFFFLPVFCLTVLYSLIGRKLWRRRGDAAVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFKLLGFESFSQRKLSTLKDESSRAWTKSSINT
  
Inhibitor
Name:
BDBM50096215
Synonyms:
CHEMBL3593815
Type:
Small organic molecule
Emp. Form.:
C28H27F2N3O4
Mol. Mass.:
507.5285
SMILES:
Cc1ccc(CNC(=O)c2cc(cnc2NCc2ccc3OCOc3c2)C#CC(C)(C)O)cc1C(F)F
Structure:
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