Reaction Details Report a problem with these data
Target
Carbonic anhydrase 1
Ligand
BDBM60995
Substrate
n/a
Meas. Tech.
ChEMBL_1446410 (CHEMBL3375524)
Ki
700±n/a nM
Citation
 Del Prete, S; Vullo, D; Fisher, GM; Andrews, KT; Poulsen, SA; Capasso, C; Supuran, CT Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum--theż-carbonic anhydrases. Bioorg Med Chem Lett 24:4389-96 (2014) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 1
Synonyms:
CA-I | CA1 | CAB | CAH1_HUMAN | Carbonate dehydratase I | Carbonic anhydrase | Carbonic anhydrase 1 (CA I) | Carbonic anhydrase 1 (CA-I) | Carbonic anhydrase 1 (Recombinant CA I) | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase B | Carbonic anhydrase I | Carbonic anhydrase I (CA I) | Carbonic anhydrase I (CA-I) | Carbonic anhydrase I (CAI) | Carbonic anhydrase I (hCA I) | Carbonic anhydrase isoenzyme I (hCA I) | hCA
Type:
Enzyme
Mol. Mass.:
28873.37
Organism:
Homo sapiens (Human)
Description:
P00915
Residue:
261
Sequence:
MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGRTVRASF
  
Inhibitor
Name:
BDBM60995
Synonyms:
BDBM50401535 | CNO- | fulminate ion
Type:
n/a
Emp. Form.:
CNO
Mol. Mass.:
42.0173
SMILES:
[O-][N+]#[C-]
Structure:
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