Reaction Details Report a problem with these data
Target
Neuromedin-U receptor 2
Ligand
BDBM50102656
Substrate
n/a
Meas. Tech.
ChEMBL_1442319 (CHEMBL3377680)
EC50
14000±n/a nM
Citation
 Ma, ML; Li, M; Gou, JJ; Ruan, TY; Jin, HS; Zhang, LH; Wu, LC; Li, XY; Hu, YH; Wen, K; Zhao, Z Design, synthesis and biological activity of flavonoid derivatives as selective agonists for neuromedin U 2 receptor. Bioorg Med Chem 22:6117-23 (2014) [PubMed]  Article 
Target
Name:
Neuromedin-U receptor 2
Synonyms:
G-protein coupled receptor FM-4 | G-protein coupled receptor TGR-1 | NMU-R2 | NMU2R | NMU2R | NMUR2 | NMUR2_HUMAN | Neuromedin-U receptor 2 | TGR1
Type:
PROTEIN
Mol. Mass.:
47710.86
Organism:
Homo sapiens (Human)
Description:
ChEMBL_103075
Residue:
415
Sequence:
MSGMEKLQNASWIYQQKLEDPFQKHLNSTEEYLAFLCGPRRSHFFLPVSVVYVPIFVVGVIGNVLVCLVILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEMWRNYPFLFGPVGCYFKTALFETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRALRILGIVWGFSVLFSLPNTSIHGIKFHYFPNGSLVPGSATCTVIKPMWIYNFIIQVTSFLFYLLPMTVISVLYYLMALRLKKDKSLEADEGNANIQRPCRKSVNKMLFVLVLVFAICWAPFHIDRLFFSFVEEWSESLAAVFNLVHVVSGVFFYLSSAVNPIIYNLLSRRFQAAFQNVISSFHKQWHSQHDPQLPPAQRNIFLTECHFVELTEDIGPQFPCQSSMHNSHLPAALSSEQMSRTNYQSFHFNKT
  
Inhibitor
Name:
BDBM50102656
Synonyms:
CHEMBL3343015
Type:
Small organic molecule
Emp. Form.:
C15H8BrFO3
Mol. Mass.:
335.125
SMILES:
Oc1c(oc2ccccc2c1=O)-c1cc(Br)ccc1F
Structure:
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