Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50102727
Substrate
n/a
Meas. Tech.
ChEMBL_1443127 (CHEMBL3371687)
EC50
6.0±n/a nM
Citation
 Abdel-Magid, AF Modulators of GPR40 as Treatment for Diabetes. ACS Med Chem Lett 5:954-5 (2014) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50102727
Synonyms:
CHEMBL3330550
Type:
Small organic molecule
Emp. Form.:
C33H31FN2O3
Mol. Mass.:
522.6092
SMILES:
COc1ccc(F)c(c1)-c1ccc(Cc2ccc(cc2)N2N=C(C(C)C2CC(O)=O)c2ccccc2)c(C)c1 |c:23|
Structure:
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