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Target
Indoleamine 2,3-dioxygenase 1
Ligand
BDBM50102732
Substrate
n/a
Meas. Tech.
ChEMBL_1443129 (CHEMBL3371689)
IC50
100±n/a nM
Citation
 Abdel-Magid, AF Indoleamine 2,3-dioxygenase inhibitors: potential treatment for cancer, sepsis, and more. ACS Med Chem Lett 5:958-60 (2014) [PubMed]  Article 
Target
Name:
Indoleamine 2,3-dioxygenase 1
Synonyms:
I23O1_HUMAN | IDO | IDO-1 | IDO1 | INDO | Indoleamine 2,3-Dioxygenasae (IDO) | Indoleamine 2,3-dioxygenase | Indoleamine-pyrrole 2,3-dioxygenase
Type:
Enzyme
Mol. Mass.:
45330.80
Organism:
Homo sapiens (Human)
Description:
P14902
Residue:
403
Sequence:
MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG
  
Inhibitor
Name:
BDBM50102732
Synonyms:
CHEMBL3335711
Type:
Small organic molecule
Emp. Form.:
C9H6ClN5
Mol. Mass.:
219.63
SMILES:
Clc1ccc(Nc2cn[nH]n2)cc1C#N
Structure:
Search PDB for entries with ligand similarity: