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Target
Alpha-1B adrenergic receptor
Ligand
BDBM50103892
Substrate
n/a
Meas. Tech.
ChEMBL_1436284 (CHEMBL3387784)
Ki
148±n/a nM
Citation
 Chen, J; Campbell, AP; Urmi, KF; Wakelin, LP; Denny, WA; Griffith, R; Finch, AM Human alpha1-adrenoceptor subtype selectivity of substituted homobivalent 4-aminoquinolines. Bioorg Med Chem 22:5910-6 (2014) [PubMed]  Article 
Target
Name:
Alpha-1B adrenergic receptor
Synonyms:
ADA1B_HUMAN | ADRA1B | Adrenergic alpha1B | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1B-adrenoceptor | Alpha 1B-adrenoreceptor | Alpha-1B adrenergic receptor
Type:
Enzyme
Mol. Mass.:
56862.13
Organism:
Homo sapiens (Human)
Description:
P35368
Residue:
520
Sequence:
MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRTLPSASPSPGYLGRGAPPPVELCAFPEWKAPGALLSLPAPEPPGRRGRHDSGPLFTFKLLTEPESPGTDGGASNGGCEAAADVANGQPGFKSNMPLAPGQF
  
Inhibitor
Name:
BDBM50103892
Synonyms:
CHEMBL3343981
Type:
Small organic molecule
Emp. Form.:
C27H32N4O2
Mol. Mass.:
444.5686
SMILES:
COc1ccc2nccc(NCCCCCCCNc3ccnc4ccc(OC)cc34)c2c1
Structure:
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