Reaction Details Report a problem with these data
Target
Free fatty acid receptor 2
Ligand
BDBM50107303
Substrate
n/a
Meas. Tech.
ChEMBL_1508993 (CHEMBL3602373)
EC50
>10000±n/a nM
Citation
 Zahanich, I; Kondratov, I; Naumchyk, V; Kheylik, Y; Platonov, M; Zozulya, S; Krasavin, M Phenoxymethyl 1,3-oxazoles and 1,2,4-oxadiazoles as potent and selective agonists of free fatty acid receptor 1 (GPR40). Bioorg Med Chem Lett 25:3105-11 (2015) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 2
Synonyms:
FFA2 | FFAR2 | FFAR2_HUMAN | G-protein coupled receptor 43 | GPCR43 | GPR43
Type:
PROTEIN
Mol. Mass.:
37156.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508993
Residue:
330
Sequence:
MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLLLLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLSRRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVRLELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTLLNFLVCFGPYNVSHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE
  
Inhibitor
Name:
BDBM50107303
Synonyms:
CHEMBL3601003
Type:
Small organic molecule
Emp. Form.:
C18H15ClN2O4
Mol. Mass.:
358.776
SMILES:
OC(=O)CCc1ccc(OCc2nc(no2)-c2ccc(Cl)cc2)cc1
Structure:
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