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Target
Somatostatin receptor type 3
Ligand
BDBM50110461
Substrate
n/a
Meas. Tech.
ChEMBL_1510034 (CHEMBL3606126)
Ki
2.0±n/a nM
Citation
 Lai, Z; He, S; Sherer, EC; Wu, Z; Yu, Y; Ball, R; Hong, Q; Yang, DX; Guo, L; Li, D; Tuang, Q; Chicchi, GG; Trusca, D; Tsao, KL; Zhou, YP; Howard, AD; Nargund, RP; Hagmann, WK Discovery of substituted (4-phenyl-1H-imidazol-2-yl)methanamine as potent somatostatin receptor 3 agonists. Bioorg Med Chem Lett 25:3520-5 (2015) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 3
Synonyms:
SOMATOSTATIN SST3 | SS-3-R | SS3-R | SS3R | SSR-28 | SSR3_HUMAN | SSTR3 | Somatostatin receptor type 3 (SSTR3)
Type:
Protein
Mol. Mass.:
45855.97
Organism:
Homo sapiens (Human)
Description:
P32745
Residue:
418
Sequence:
MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
  
Inhibitor
Name:
BDBM50110461
Synonyms:
CHEMBL3605789
Type:
Small organic molecule
Emp. Form.:
C23H23FN4
Mol. Mass.:
374.4539
SMILES:
Fc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1c[nH]c2ccccc12
Structure:
Search PDB for entries with ligand similarity: