Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50111766
Substrate
n/a
Meas. Tech.
ChEMBL_1510663 (CHEMBL3608114)
Ki
3.9±n/a nM
Citation
 Cao, Y; Paudel, S; Zhang, X; Kim, KM; Cheon, SH Synthesis and evaluation of arylpiperazine-reverse amides as biased dopamine D3 receptor ligands. Bioorg Med Chem 23:5264-72 (2015) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50111766
Synonyms:
CHEMBL3605331
Type:
Small organic molecule
Emp. Form.:
C22H25FN4OS
Mol. Mass.:
412.524
SMILES:
Fc1ccccc1N1CCN(CCCCC(=O)Nc2nc3ccccc3s2)CC1
Structure:
Search PDB for entries with ligand similarity: