Target
Melatonin receptor type 1A
Ligand
BDBM50117880
Substrate
n/a
Meas. Tech.
ChEMBL_1514064 (CHEMBL3614202)
Ki
5.3±n/a nM
Citation
 Spadoni, GBedini, ALucarini, SMari, MCaignard, DHBoutin, JADelagrange, PLucini, VScaglione, FLodola, AZanardi, FPala, DMor, MRivara, S Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines. J Med Chem 58:7512-25 (2015) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50117880
Synonyms:
CHEMBL3612462
Type:
Small organic molecule
Emp. Form.:
C14H21N3O
Mol. Mass.:
247.336
SMILES:
CCNC(=O)NCC1CCc2ccccc2N1C
Structure:
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