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TargetBirA bifunctional protein
LigandBDBM50119307
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1515555
Kd 0.153000±n/a nM
Citation Bockman, MRKalinda, ASPetrelli, RDe la Mora-Rey, TTiwari, DLiu, FDawadi, SNandakumar, MRhee, KYSchnappinger, DFinzel, BCAldrich, CC Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors. J Med Chem58:7349-69 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
BirA bifunctional protein
Name:BirA bifunctional protein
Synonyms:birA
Type:PROTEIN
Mol. Mass.:28120.21
Organism:Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Description:ChEMBL_107988
Residue:266
Sequence:
MTDRDRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIA
EHQTAGRGRHGRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVP
PAETGLKWPNDVLARGGKLAGILAEVAQPFVVLGVGLNVTQAPEEVDPDATSLLDLGVAA
PDRNRIASRLLRELEARIIQWRNANPQLAADYRARSLTIGSRVRVELPGGQDVVGIARDI
DDQGRLCLDVGGRTVVVSAGDVVHLR
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50119307
NameBDBM50119307
Synonyms:CHEMBL3613835
TypeSmall organic molecule
Emp. Form.C26H42FN9O7S2
Mol. Mass.675.796
SMILESCC[NH+](CC)CC.[H][C@]12CS[C@@H](CCCCC(=O)[N-]S(=O)(=O)OC[C@H]3O[C@H]([C@@H](F)[C@@H]3O)n3cnc4c(N)ncnc34)[C@@]1([H])NC(=O)N2 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a