Reaction Details Report a problem with these data
Target
Histamine receptor H4
Ligand
BDBM50006789
Substrate
n/a
Meas. Tech.
ChEMBL_1521728 (CHEMBL3626551)
Ki
306±n/a nM
Citation
 Tichenor, MS; Thurmond, RL; Venable, JD; Savall, BM Functional Profiling of 2-Aminopyrimidine Histamine H4 Receptor Modulators. J Med Chem 58:7119-27 (2015) [PubMed]  Article 
Target
Name:
Histamine receptor H4
Synonyms:
HISTAMINE H4 | HRH4 | Histamine H4 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44536.99
Organism:
GUINEA PIG
Description:
HISTAMINE H4 HRH4 GUINEA PIG::Q91ZY3
Residue:
389
Sequence:
MLANNSTIALTSIKISLTFLMSLLAIAIMLGNVVVILAFIVDRNLRHRSNYFFLNLAIADFFVGAIAIPLYIPSSLTYWTSGKQACVFWLITDYLLCTASVYNIVLISYDRYQSVSNAVWYRAQHSGTWKIATQMVAVWIFSFMTNGPMILISDSWQNSTTECEPGFLKKWYFALPTSLLEFLIPILLVAYFSAHIYWSLWKREKLSRCLSHPVLPSDSSSSDHGHSCRQDPDSRATLPARKETTASLGSDKSRRKSSLLFSIRAYKNSNVIASKMGFLSHSDSLALQQREHIELFRARKLAKSLAILLAAFAICWAPYSLTTVIYSFFPERNLTKSTWYHTAFWLQWFNSFVNPFLYPLCHKRFQKAFLKILPVRRQSTPPHNRSIST
  
Inhibitor
Name:
BDBM50006789
Synonyms:
CHEMBL3236549
Type:
Small organic molecule
Emp. Form.:
C11H19N5
Mol. Mass.:
221.3021
SMILES:
CC(C)c1cc(nc(N)n1)N1CC[C@@H](N)C1 |r|
Structure:
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