Reaction Details Report a problem with these data
Target
Prokineticin receptor 1
Ligand
BDBM50121329
Substrate
n/a
Meas. Tech.
ChEMBL_1522243 (CHEMBL3626472)
IC50
>9000±n/a nM
Citation
 Abdel-Magid, AF Prokineticin Receptor Modulators May Potentially Treat Psychiatric and Neurological Disorders. ACS Med Chem Lett 6:834-5 (2015) [PubMed]  Article 
Target
Name:
Prokineticin receptor 1
Synonyms:
G-protein coupled receptor 73 | G-protein coupled receptor ZAQ | GPR73 | GPR73a | PK-R1 | PKR1 | PKR1_HUMAN | PROKR1
Type:
enzyme
Mol. Mass.:
44779.92
Organism:
Homo sapiens (Human)
Description:
Q8TCW9
Residue:
393
Sequence:
METTMGFMDDNATNTSTSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFFAAKIVIGMALVGIMLVCGIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTATGLIALVWTVSILIAIPSAYFTTETVLVIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGIEFVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFPTVFVKEKHYLTAFYIVECIAMSNSMINTLCFVTVKNDTVKYFKKIMLLHWKASYNGGKSSADLDLKTIGMPATEEVDCIRLK
  
Inhibitor
Name:
BDBM50121329
Synonyms:
CHEMBL3622091 | US10562882, Example 42
Type:
Small organic molecule
Emp. Form.:
C17H22ClN5O2
Mol. Mass.:
363.842
SMILES:
COC1(CCCN(C1)C(=O)c1cn(C)nc1N)c1ncc(Cl)cc1C
Structure:
Search PDB for entries with ligand similarity: