Reaction Details Report a problem with these data
Target
RCG38204, isoform CRA_d
Ligand
BDBM14673
Substrate
n/a
Meas. Tech.
ChEMBL_1517183 (CHEMBL3620073)
Ki
1562000±n/a nM
Citation
 Katane, M; Yamada, S; Kawaguchi, G; Chinen, M; Matsumura, M; Ando, T; Doi, I; Nakayama, K; Kaneko, Y; Matsuda, S; Saitoh, Y; Miyamoto, T; Sekine, M; Yamaotsu, N; Hirono, S; Homma, H Identification of Novel D-Aspartate Oxidase Inhibitors by in Silico Screening and Their Functional and Structural Characterization in Vitro. J Med Chem 58:7328-40 (2015) [PubMed]  Article 
Target
Name:
RCG38204, isoform CRA_d
Synonyms:
D-aspartate oxidase | Ddo | Ensembl:ENSRNOP00000000710 | LOC100911156 | Protein Ddo | RCG38204, isoform CRA_d | RGD:1595123
Type:
PROTEIN
Mol. Mass.:
37549.70
Organism:
Rattus norvegicus
Description:
ChEMBL_109876
Residue:
341
Sequence:
MDTVRIAVVGAGVIGLSTAACVSQLVPRCSVTVISDRFTPDTTSNVAAGMLIPPTYPDTPVPTLKRWFRETFQHLSEIARSAEAVDAGIHLVSGWQIFRSVPTEEVPFWADVVLGFREMTEAELKRFPQYEFGQAFTTLKCETSAYLPWLEKRIKGSGGLLLTRRIEDLWELQPSFDIVVNCSGLGSRRLVGDATVSPVRGQVLQAQAPWVKHFIRDGGGLTYVYPGTSYVTLGGSRQTGDWNLSPDAELSREIFSRCCALEPSLHRACDIKEKVGLRPSRPGVRLQKEILVRGEQRLPVVHNYGHGSGGISVHWGSALEATRLVMECVHTLRTPASLSKL
  
Inhibitor
Name:
BDBM14673
Synonyms:
Fragment 3 | Malonic Acid | propanedioic acid
Type:
Small organic molecule
Emp. Form.:
C3H4O4
Mol. Mass.:
104.0615
SMILES:
OC(=O)CC(O)=O
Structure:
Search PDB for entries with ligand similarity: