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Target
D-aspartate oxidase
Ligand
BDBM14673
Substrate
n/a
Meas. Tech.
ChEMBL_1517182 (CHEMBL3620072)
Ki
153000±n/a nM
Citation
 Katane, M; Yamada, S; Kawaguchi, G; Chinen, M; Matsumura, M; Ando, T; Doi, I; Nakayama, K; Kaneko, Y; Matsuda, S; Saitoh, Y; Miyamoto, T; Sekine, M; Yamaotsu, N; Hirono, S; Homma, H Identification of Novel D-Aspartate Oxidase Inhibitors by in Silico Screening and Their Functional and Structural Characterization in Vitro. J Med Chem 58:7328-40 (2015) [PubMed]  Article 
Target
Name:
D-aspartate oxidase
Synonyms:
D-Aspartate Oxidase (DDO) | DASOX | DDO | OXDD_HUMAN
Type:
Oxidoreductase
Mol. Mass.:
37543.06
Organism:
Homo sapiens (Human)
Description:
Recombinant human DDO expressed and purified from sf9 insect cells, was used in enzyme assays.
Residue:
341
Sequence:
MDTARIAVVGAGVVGLSTAVCISKLVPRCSVTIISDKFTPDTTSDVAAGMLIPHTYPDTPIHTQKQWFRETFNHLFAIANSAEAGDAGVHLVSGWQIFQSTPTEEVPFWADVVLGFRKMTEAELKKFPQYVFGQAFTTLKCECPAYLPWLEKRIKGSGGWTLTRRIEDLWELHPSFDIVVNCSGLGSRQLAGDSKIFPVRGQVLQVQAPWVEHFIRDGSGLTYIYPGTSHVTLGGTRQKGDWNLSPDAENSREILSRCCALEPSLHGACNIREKVGLRPYRPGVRLQTELLARDGQRLPVVHHYGHGSGGISVHWGTALEAARLVSECVHALRTPIPKSNL
  
Inhibitor
Name:
BDBM14673
Synonyms:
Fragment 3 | Malonic Acid | propanedioic acid
Type:
Small organic molecule
Emp. Form.:
C3H4O4
Mol. Mass.:
104.0615
SMILES:
OC(=O)CC(O)=O
Structure:
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