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Target
Catalase
Ligand
BDBM50127136
Substrate
n/a
Meas. Tech.
ChEMBL_1524705 (CHEMBL3631099)
IC50
>10000±n/a nM
Citation
 Wu, JS; Lin, SY; Liao, FY; Hsiao, WC; Lee, LC; Peng, YH; Hsieh, CL; Wu, MH; Song, JS; Yueh, A; Chen, CH; Yeh, SH; Liu, CY; Lin, SY; Yeh, TK; Hsu, JT; Shih, C; Ueng, SH; Hung, MS; Wu, SY Identification of Substituted Naphthotriazolediones as Novel Tryptophan 2,3-Dioxygenase (TDO) Inhibitors through Structure-Based Virtual Screening. J Med Chem 58:7807-19 (2015) [PubMed]  Article 
Target
Name:
Catalase
Synonyms:
CAT | CATA_HUMAN | Catalase
Type:
PROTEIN
Mol. Mass.:
59764.51
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109916
Residue:
527
Sequence:
MADSRDPASDQMQHWKEQRAAQKADVLTTGAGNPVGDKLNVITVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLSQEDPDYGIRDLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPSNMPPGIEASPDKMLQGRLFAYPDTHRHRLGPNYLHIPVNCPYRARVANYQRDGPMCMQDNQGGAPNYYPNSFGAPEQQPSALEHSIQYSGEVRRFNTANDDNVTQVRAFYVNVLNEEQRKRLCENIAGHLKDAQIFIQKKAVKNFTEVHPDYGSHIQALLDKYNAEKPKNAIHTFVQSGSHLAAREKANL
  
Inhibitor
Name:
BDBM50127136
Synonyms:
CHEMBL1442185
Type:
Small organic molecule
Emp. Form.:
C18H13N3O2
Mol. Mass.:
303.3147
SMILES:
Cc1ccccc1Cn1nnc2c1C(=O)c1ccccc1C2=O
Structure:
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