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Target
Serine/threonine-protein kinase pim-2
Ligand
BDBM50131265
Substrate
n/a
Meas. Tech.
ChEBML_1526829
Ki
0.430000±n/a nM
Citation
 Hu, H; Wang, X; Chan, GK; Chang, JH; Do, S; Drummond, J; Ebens, A; Lee, W; Ly, J; Lyssikatos, JP; Murray, J; Moffat, JG; Chao, Q; Tsui, V; Wallweber, H; Kolesnikov, A Discovery of 3,5-substituted 6-azaindazoles as potent pan-Pim inhibitors. Bioorg Med Chem Lett 25:5258-64 (2015) [PubMed]  Article 
Target
Name:
Serine/threonine-protein kinase pim-2
Synonyms:
PIM2 | PIM2_HUMAN | Pim-2h | Serine/threonine-protein kinase (PIM2) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase pim-2 (PIM2)
Type:
Serine/threonine-protein kinase
Mol. Mass.:
34185.93
Organism:
Homo sapiens (Human)
Description:
Q9P1W9
Residue:
311
Sequence:
MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAIKVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVPLNPSKGGPAPLAWSLLP
  
Inhibitor
Name:
BDBM50131265
Synonyms:
CHEMBL3634757 | US9260425, 189
Type:
Small organic molecule
Emp. Form.:
C19H20N8
Mol. Mass.:
360.4157
SMILES:
Cn1cc(cn1)-c1cc2c(n[nH]c2cn1)-c1cccc(n1)N1CC[C@@H](N)C1 |r|
Structure:
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