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Target
Probable G-protein coupled receptor 139
Ligand
BDBM50132137
Substrate
n/a
Meas. Tech.
ChEMBL_1526933 (CHEMBL3637279)
EC50
24±n/a nM
Citation
 Dvorak, CA; Coate, H; Nepomuceno, D; Wennerholm, M; Kuei, C; Lord, B; Woody, D; Bonaventure, P; Liu, C; Lovenberg, T; Carruthers, NI Identification and SAR of Glycine Benzamides as Potent Agonists for the GPR139 Receptor. ACS Med Chem Lett 6:1015-8 (2015) [PubMed]  Article 
Target
Name:
Probable G-protein coupled receptor 139
Synonyms:
G(q)-coupled orphan receptor GPRg1 | G-protein coupled receptor 139 | G-protein-coupled receptor PGR3 | GP139_HUMAN | GPR139 | GPRG1 | GPRG1 | PGR3 | Probable G-protein coupled receptor 139
Type:
PROTEIN
Mol. Mass.:
40700.34
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109920
Residue:
353
Sequence:
MEHTHAHLAANSSLSWWSPGSACGLGFVPVVYYSLLLCLGLPANILTVIILSQLVARRQKSSYNYLLALAAADILVLFFIVFVDFLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTRKVIVSVYITCFLTSIPYYWWPNIWTEDYISTSVHHVLIWIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATLWAPRIIMILYHLYGAPIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFRTMAAATLKAFFKCQKQPVQFYTNHNFSITSSPWISPANSHCIKMLVYQYDKNGKPIKVSP
  
Inhibitor
Name:
BDBM50132137
Synonyms:
CHEMBL3633878
Type:
Small organic molecule
Emp. Form.:
C18H20N2O2
Mol. Mass.:
296.3636
SMILES:
C[C@H](NC(=O)CNC(=O)c1cccc(C)c1)c1ccccc1 |r|
Structure:
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